Manchester United head into the second leg of their Europa League quarter final level with Anderlecht, 1-1 on aggregate.
With a finish in the Premier League’s top four looking difficult to achieve, its Europe or bust if Man Utd are to feature in next season’s Champions League.
Sergio Romero will start in goal for the Red Devils ahead of David de Gea.
Wayne Rooney is expected to be named on the bench after overcoming an ankle injury.
Jose Mourinho is definitely without Phil Jones (foot), Juan Mata (groin) and Chris Smalling (knee) for this match.
Anderlecht have a fully fit squad but could be without fullback, Andy Najar.
All signs point towards an United victory in this tie.
The visitors are yet to secure an away victory at Old Trafford and with Zlatan Ibrahimovic fresh after making a substitute appearance against Chelsea on Sunday, it will be tougher.
So far this season, Manchester United are yet to suffer defeat at home in Europe. In fact, they are yet to lose at home since their loss to Real Madrid in the 2012-13 Champions League season under Sir Alex Ferguson.
Anderlecht might of lost just one European game this season but are without victory in 15 trips to England.
Rene Weller and his side might have a great away record but can see it ending here.
The Red Devils will be too strong and with no away victory over here, it be a shock if the Belgian side progressed.
United should cruise through here after a frustrating first leg.
Prediction: Manchester United 2-0 Anderlecht
Result: Manchester United 2-1 Anderlecht (United progress 3-2 on aggregate)